Cytochrome P-450 CYP2E1

An ethanol-inducible cytochrome P450 enzyme that metabolizes several precarcinogens, drugs, and solvents to reactive metabolites. Substrates include ETHANOL; INHALATION ANESTHETICS; BENZENE; ACETAMINOPHEN and other low molecular weight compounds. CYP2E1 has been used as an enzyme marker in the study of alcohol abuse.

Also Known As:

CYP2E1; CYP 2E1; CYP IIE1; CYPIIE1; Cytochrome P-450 (ALC); Cytochrome P-450 IIE1; Cytochrome P-450-J; Cytochrome P450 2E1; N-Nitrosodimethylamine Demethylase; 4 Nitrophenol 2 Hydroxylase; Cytochrome P 450 CYP2E1; Cytochrome P 450 IIE1; Cytochrome P 450 J; Dimethylnitrosamine N Demethylase; N Nitrosodimethylamine Demethylase; 4-Nitrophenol-2-Hydroxylase; Dimethylnitrosamine N-Demethylase

Enzymes and Coenzymes: 1
- Enzymes: 155591
  - Oxidoreductases: 13899
    - Oxygenases: 336
      - Mixed Function Oxygenases: 2207
        Cytochrome P-450 Enzyme System: 5452
        Cytochrome P450 Family 2: 33
        Cytochrome P-450 CYP2E1: 1326
    - Oxidoreductases Acting on CH-NH Group Donors
      - N-Demethylating Oxidoreductases: 18
        Cytochrome P-450 CYP2E1: 1326
- Cytochromes: 2210
  - Cytochrome P-450 Enzyme System: 5452
    - Cytochrome P450 Family 2: 33
      - Cytochrome P-450 CYP2E1: 1326
Amino Acids, Peptides, and Proteins: 1
- Proteins: 496323
  - Hemeproteins: 196
    - Cytochromes: 2210
      - Cytochrome P-450 Enzyme System: 5452
        Cytochrome P450 Family 2: 33
        Cytochrome P-450 CYP2E1: 1326

Zihuan Li Selected Research

Zihuan Li Research Topics

Disease

Drug/Important Bio-Agent (IBA)